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10.1007/s00204-009-0436-9 Arch

Among its extra-pancreatic effects, GLP-1 decreases gastric acid secretion directly by inhibition of parietal cells and indirectly by stimulation of somatostatin (SST) secretion by D cells 10,11,12

Phase 3 data: TRIUMPH-4 The TRIUMPH-4 trial focused on participants with osteoarthritis and demonstrated an average weight loss of 71.2 pounds along with significant improvements in joint pain and function